The discovery could lead to a new generation of drugs for non-invasive intranasal for dental pain, and other conditions, scientists suggest American Chemical Society journal Molecular Pharmacy bimonthly. The article is scheduled for review in May or June.Modern dentistry has eliminated much of the ‘ouch!’ to get a shot of local anesthetic. Now a new discovery may change the needle used to give a local anesthetic the dentist’s chair for many procedures. Scientists test a common local anesthetic, if administered to the nose as nasal drops or nasal spray, travel through the main nerve in the face and collects in high concentrations, teeth and jaw structures of the mouth.
Article: ‘the ways of the trigeminal delivering a drug with low molecular weight from the nose to the brain structures and orofacial’
William H. Frey II, Ph.D., and colleagues note that the drugs given to travel along the nerves of the nose and go to the brain. One of these is the trigeminal nerve, which carries a sense on the face, nose and mouth. So far, however, scientists have never checked to see if the drugs intranasally to pass along the nerve, teeth, gums and other areas of the face and mouth to reduce pain sensations in the face and mouth.